The project involves:

• Two University Hospitals:
  • Hospices Civils de Lyon (HCL), the project coordinator institution, is in charge of the pre-clinical phase and of the clinical investigation aimed at producing evidence of efficacy and safety of the implant on the targeted mitral regurgitation population.
  • CHU de Saint-Étienne (CHUSE) is in charge of the functional evaluation of the implantation of the ICELAND device for mitral valve repair.
• Five academic partners:
  • Université Claude Bernard Lyon 1 (UCBL) 
  • Ecole Centrale de Lyon (ECL) is in charge of the experimental validation of the fixation of the implant on the mitral valve annulus 
  • INSA Lyon is in charge of several tasks :
    • Numerical simulation of the treated valve
    • Experimental validation of the anchoring solution 
    • Numerical simulation of the surgical procedure for surgeons training and surgery optimization 
    • Evaluation of the device’s biocompatibility
  • Centre National de la Recherche Scientifique (CNRS) is in charge of pre-operative and intra-operative image fusion to :
    • Assist with the surgery planning and the positioning of the surgical anchors
    • Secure the intervention by using pre and per-operative information to motorize the robot. 
  • Sorbonne Université (SU) is in charge of the robotization of the delivery system and of guiding the robotic instrument owing to different imaging modalities
•  A private company:
  • DigiSurge develops the annuloplasty implant, the mechatronics catheter and delivery systems, the robotic platform integration, and will be in charge of market access and commercialization.